2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-119850A
    Aladorian sodium 1233219-11-8 98%
    Aladorian (ARM036) sodium is a benzothiazepine derivative, with anti-arrhythmia effect. Aladorian sodium is a ryanodine receptor (RyR2) blocker. Aladorian sodium is used for the research of heart failure and catecholaminergic polymorphic ventricular tachycardia.
    Aladorian sodium
  • HY-119926A
    13-Hydroxylupanine hydrochloride 6809-89-8 98%
    13-Hydroxylupanine Hydroxylupanine is the typical alkaloid profile of sweet lupins. 13-Hydroxylupanine Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle.
    13-Hydroxylupanine hydrochloride
  • HY-120611A
    BMS-960 1265323-40-7 98%
    BMS-960 is a potent and selective S1P1 receptor agonist containing isoxazole, which can be used in the research of immune diseases and vascular diseases.
    BMS-960
  • HY-120657R
    9-PAHSA (Standard) 1481636-31-0
    Flumethrin (Standard) is the analytical standard of Flumethrin. This product is intended for research and analytical applications. Flumethrin is an active compound.
    9-PAHSA (Standard)
  • HY-121382R
    Gypsogenin (Standard) 639-14-5
    Cinosulfuron (Standard) is the analytical standard of Cinosulfuron. This product is intended for research and analytical applications. Cinosulfuron is a selective herbicide with excellent inhibitory activity against a variety of broadleaf weeds and is widely used in crop fields to protect the growth of crops. Cinosulfuron can effectively manage weed problems by inhibiting specific enzyme activity. Cinosulfuron is used in agriculture to increase crop yield and quality and ensure efficient use of farmland.
    Gypsogenin (Standard)
  • HY-121385S
    Hydroxy Bosentan-d6 1246817-57-1 98%
    Hydroxy Bosentan-d6 is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities.
    Hydroxy Bosentan-d6
  • HY-121453R
    Bamifylline hydrochloride (Standard) 20684-06-4
    Bamifylline (hydrochloride) (Standard) is the analytical standard of Bamifylline (hydrochloride). This product is intended for research and analytical applications. Bamifylline hydrochloride is a drug in the chemical class of xanthine that acts as a selective adenosine A1 receptor antagonist.
    Bamifylline hydrochloride (Standard)
  • HY-121609A
    Pholedrine hydrochloride 877-86-1 99.63%
    Pholedrine hydrochloride, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine hydrochloride is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine hydrochloride can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine hydrochloride can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome.
    Pholedrine hydrochloride
  • HY-12176AS
    Aliskiren-d6 hydrochloride 1246815-96-2 98%
    Aliskiren-d6 (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor.
    Aliskiren-d6 hydrochloride
  • HY-121814A
    (R)-Acenocoumarol 66556-77-2 98%
    (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting and orally active anticoagulant, like Warfarin (HY-B0687), works by inhibiting vitamin K epoxide reductase. (R)-Acenocoumarol has a greater in vivo anticoagulant potency than Warfarin. (R)-Acenocoumarol has a single chiral center that produces two different enantiomeric forms. (R)-Acenocoumarol has a longer plasma elimination half-life (6.6 h) and a slower plasma clearance rate (1.9 L/h) than the (S)-enantiomer, resulting in a stronger in vivo anticoagulant effect.
    (R)-Acenocoumarol
  • HY-121936R
    Yohimbic acid (Standard) 522-87-2
    Hexyl methanesulfonate (Standard) is the analytical standard of Hexyl methanesulfonate. This product is intended for research and analytical applications. Hexyl methanesulfonate (Methanesulfonic acid hexyl ester) is an ester product.
    Yohimbic acid (Standard)
  • HY-122525A
    Sabiporide hydrochloride 324758-66-9 98%
    Sabiporide hydrochloride is a NHE-1 inhibitor (Ki: 50 nM). Sabiporide hydrochloride has cardioprotective and neuroprotective effects. Sabiporide hydrochloride inhibits glutamate- or NMDA-induced neuronal cell death.
    Sabiporide hydrochloride
  • HY-122525B
    Sabiporide mesylate 261505-81-1 98%
    Sabiporide (BIIB 722 mesylate) mesylate is a selective inhibitor of sodium-hydrogen exchange, known for its cardioprotective properties, making it a valuable tool for investigating myocardial ischemia and myocardial infarction.
    Sabiporide mesylate
  • HY-122542A
    PPACK dihydrochloride 82188-90-7 98%
    PPACK dihydrochloride is potent, selective and irreversible thrombin inhibitor. PPACK dihydrochloride can be used an alternative anticoagulant to lithium heparin (LiHep) for blood gas and whole-blood electrolyte analyses. PPACK dihydrochloride is also a plasminogen activator (rt-PA) inhibitor. PPACK dihydrochloride can inhibit the binding of rt-PA to plasma protease inhibitors.
    PPACK dihydrochloride
  • HY-122543A
    PPACK II 74392-49-7 98%
    PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor.
    PPACK II
  • HY-122778R
    δ-Tocotrienol (Standard) 25612-59-3
    δ-Tocotrienol (Standard) is the analytical standard of δ-Tocotrienol. This product is intended for research and analytical applications. δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.
    δ-Tocotrienol (Standard)
  • HY-122792R
    Phenyramidol Hydrochloride (Standard) 326-43-2
    Phenyramidol (Hydrochloride) (Standard) is the analytical standard of Phenyramidol (Hydrochloride). This product is intended for research and analytical applications. Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak.
    Phenyramidol Hydrochloride (Standard)
  • HY-123400A
    iso-Samixogrel 133276-52-5 98%
    Iso-Samixogrel (iso-DTTX30) is a combined thromboxane A2 receptor blocker and thromboxane synthetase inhibitor that exhibits potent antithrombotic activity. Iso-Samixogrel effectively eliminates recurrent arterial thrombus formation and inhibits collagen-induced platelet aggregation ex vivo. Iso-Samixogrel also prolongs sublingual bleeding time, demonstrating its biological efficacy in managing thrombosis.
    iso-Samixogrel
  • HY-123449A
    MK-761 TFA 99.93%
    MK-761 TFA is a potent and orally active β2-adrenergic blocker. MK-761 TFA shows antihypertensive and positive inotropic effects. MK-761 TFA shows vasodilating properties.
    MK-761 TFA
  • HY-125101A
    Rafutrombopag diolamine 1257792-42-9 98%
    Rafutrombopag diolamine is the derivative of Rafutrombopag. Rafutrombopag is a thrombopoietin receptor agonist.
    Rafutrombopag diolamine
Cat. No. Product Name / Synonyms Application Reactivity